Stapgen is a pioneering MedTech/Biotech company in preventive care of Type 2 Diabetes founded by two brothers in Boston who came from South Asia overcoming significant poverty and disadvantages to achieve success. Educated at prestigious western universities, one brother is now a world-renowned researcher, and the other a successful dentist. Together, they are driven by a mission to prevent Type 2 Diabetes and a vision of a world free from the disease.
Based in Boston, MA, Stapgen is at the forefront of preventive care for Type 2 Diabetes with its groundbreaking STAP-Test. This patented technology measures intestinal alkaline phosphatase (IAP) level in the stool, enabling early diagnosis of incipient diabetes. By detecting and addressing IAP deficiency (IAPD), a know cause of Type 2 Diabetes, the STAP-Test can predict and potentially help prevent the onset of this global health crisis. With exclusive global rights to this revolutionary technology, Stapgen is poised to make a transformative impact on diabetes prevention worldwide.
Mission: to prevent Type 2 Diabetes,
Vision: to see a world without Diabetes.
STAP-Test, IAP, IAPD, Incipient Diabetes, and Early Diagnosis of T2DM - our pioneering specialty.
DETECT------->INTERCEPT--------->PREVENT
TYPE 2 DIABETES
IAP in the gut is the single most important enzyme related to Type 2 Diabetes. IAP deficiency (IAPD) causes Type 2 Diabetes. Therefore, checking your IAP level is extremely important to intercept and prevent diabetes.
Ask your primary care physician during annual check up for a STAP-Test.
2010: Intestinal alkaline phosphatase preserves the normal homeostasis of gut microbiota, Malo et el., Gut. 2010 Nov;59(11):1476-84)https://pubmed.ncbi.nlm.nih.gov/20947883/ citations: 256
2013: Intestinal alkaline phosphatase prevents metabolic syndrome in mice, Kaliannan et al. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):7003-8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637741/
2015: A High Level of Intestinal Alkaline Phosphatase Is Protective Against Type 2 Diabetes Mellitus Irrespective of Obesity, Malo, EBioMedicine,1December 2015,https://pubmed.ncbi.nlm.nih.gov/26844282/ citations: 87
2021: In a 5-year prospective cohort human study, Dr. Malo and his team proved, “IAP deficiency increases the risk of T2DM.”
Malo et al., BMJ Open Diabetes Res Care. 2022 Jan:10(1)e002643; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796214/ ;
The American Diabetes Association and the British Medical Journal jointed published the BMJ Open Diabetes Res Care journal article.
§Issued patent: Diagnosis and treatment of incipient diabetes. U.S. 10,781,470 USPTO (iss 2020), Inventor: MS Malo
Chief Scientist:
Dr. Madhu S. Malo, MBBS, PhD. He was an Assistant Professor in Harvard Medical School, and a Postdoc in MIT. He received his PhD from Sydney University, and medical degree from Dhaka Medical College. He recently discovered the root cause of Type 2 Diabetes. IAPD increases the risk of type 2 diabetes 14 times more than normal level of IAP in the gut. His discovery was published in Jan 26, 2022 in British Medical Journal, and American Diabetes Association. This discovery will change our conversation on how we take care Diabetes. Currently he is a visiting professor at BIRDEM, Dhaka, Bangladesh, and an advisor to Diabetic Association of Bangladesh.
Dr. Biplab K. Malo, DMD graduated from University of Pennsylvania, School of Dental Medicine in 2000. He was the first dentist of Bangladeshi national to graduate from UPSDM. He has been the owner of a successful Startup dental practice over a decade. He is the brother of Dr. Madhu S. Malo, MBBS, PhD. Stapgen will be his second Startup company.
Technology Advisor:
Suresh Subbu is a highly skilled and experienced technology executive, known for his exceptional leadership abilities and entrepreneurial ventures. With a rich professional background spanning over 20 years, he has effectively served renowned Fortune 500 institutions across multiple industries, including Fintech, Retail, Manufacturing, and Utilities.
In addition to his executive roles, Suresh also contributes as a board member within the startup ecosystem, actively supporting and fostering growth, as well as driving technology transformation. He brings his extensive knowledge and proficiency in Global Technology Service Delivery, Program Management, Site Reliability Engineering, Automation, Cloud, and Blockchain to help startups thrive.
Suresh is widely recognized for his expertise in leading large-scale Digital Transformations, Product Development, and Cloud Engineering Development initiatives. His deep understanding of emerging technologies and his ability to drive innovation make him a valuable asset in any organization.
Overall, Suresh Subbu's impressive track record and wealth of experience make him an ideal candidate for roles that require strategic thinking, technological acumen, and a passion for driving business growth.
Mark Norige
Mark is the Principal and CEO of Board Forum, a thriving CEO peer advisory firm. With over 30 years of business leadership expertise, Mark challenges and guides small to mid-size companies to new heights.
As an adjunct professor at respected institutions including Worcester Polytechnic Institute, Brown University, and Dean College, Mark capably merges theory with real-world practice in Product Design, Innovation, and Entrepreneurship.
A graduate of the University of Massachusetts (Engineering) and Babson College (MBA), Mark's professional journey boasts key positions at industry giants like Texas Instruments, Waters, Millipore, and Harvard Bioscience, as well as various early-stage ventures. His multifaceted roles encompass operations, product development, quality assurance, business development, and executive management.
Mark's track record speaks volumes, with over twenty successful product launches, a dozen acquisitions and license deals, and numerous successful turnarounds under his belt. His true passion lies in leveraging his wealth of experience to support emerging business leaders.
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