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Pioneering The Preventive Care For Chronic Inflammatory Diseases (CID) Using Gut-Health Technology

IAP-Biodefense
Stapgen - Revolutionizing Chronic Disease Prevention Through Gut Health

Meet Our Awesome Team

Dr. Madhu S. Malo, MBBS, PhD
Chief Scientist

Malo, MBBS, PhD. He was an Assistant Professor in Harvard Medical School, and a Postdoc in MIT.

Dr. Biplab K. Malo, DMD
Founder and CEO

Malo, DMD graduated from University of Pennsylvania, School of Dental Medicine in 2000.

Suresh Subbu
Technology Advisor

Suresh Subbu is a highly skilled and experienced technology executive

Greg Bauer
Business Communication Advisor

Health Connections- Founder. A veteran of business development, marketing and digital health solutions,

Learning

The Three Main Types of Diabetes

The Three Main Types of Diabetes

Diabetes

The Three Main Types of Diabetes

The Three Main Types of Diabetes

Our Mission

To prevent chronic inflammatory diseases (CID) including Diabetes

Our Vision

To see a healthy world

Our Pioneering Specialty: Treatment of IAPD, the root cause of CID

Early Diagnosis of T2DM

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Early diagnosis of T2DM is vital for effective management and prevention of complications.

STAP-Test

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It detects and measure intestinal alkaline phosphatase (IAP) in a stool sample. If you have no IAP you will develop Type 2 Diabetes; if you have normal level of IAP, you will not develop Type 2 Diabetes.

IAP

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IAP is the most important enzyme in the gut. We have two decades of research information on this enzyme. IAP maintains your gut health.

Discover your IAP level

IAP in the gut is the single most important enzyme related to Type 2 Diabetes.  IAP deficiency (IAPD) causes Type 2 Diabetes. Therefore, checking your IAP level is extremely important to intercept and prevent diabetes. Ask your primary care physician during annual check up for a STAP-Test.
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Our Pipeline

Pioneering in prevention of Type 2 Diabetes

Our pipeline will focus on the preventions and cure of Type 2 Diabetes, with the breakthrough diagnostics and therapeutics. We also have assets that are focusing on

  • Dementia
  • Diabetes
  • Colorectal cancer
  • Coronary artery disease
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Better Health, Brighter Future

Join Us
Work with globally diverse colleagues who are committed to bringing Better Health to people
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Investors
Discover our balanced, diverse portfolio and strategy for sustainable, patient centered
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R&D
Fueled by our inherent curiosity, we translate science into highly innovative, life-transforming.
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Your Support Means Healthier Futures for Diabetes Patients

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Diabetes is a life-changing condition that affects millions of people around the world, often leading to serious health complications. For many patients, managing diabetes requires constant care, medication, and lifestyle adjustments, which can be both physically and financially overwhelming.

Our Areas of Focus

Diabetes

Diabetes management is a critical area of focus in healthcare, given the global rise in cases of both Type 1 and Type 2 diabetes.

Cardio metabolic diseases

Cardio-metabolic diseases represent a cluster of interrelated conditions, including cardiovascular disease, type 2 diabetes, and metabolic disorders such as obesity and hypertension.

Neurodegenerative diseases

Neurodegenerative diseases are a group of disorders characterized by the progressive degeneration of nerve cells (neurons) in the brain and spinal cord.

Our Services

#1
Featured Service

STAP- Test to detect T2DM in advance prior to the rise of blood sugar.

#2
Featured Service

Supplements to prevent T2DM

#3
Featured Service

IAP-Toothpaste to prevent infant dental caries

Two Decades of Research

§Issued patent: Diagnosis and treatment of incipient diabetes. U.S. 10,781,470 USPTO (iss 2020), Inventor: MS Malo

2010
Intestinal alkaline phosphatase preserves the normal homeostasis of gut microbiota, Malo et el., Gut. 2010 Nov;59(11):1476-84 https://pubmed.ncbi.nlm.nih.gov/20947883/ citations: 256
2013
Intestinal alkaline phosphatase prevents metabolic syndrome in mice, Kaliannan et al. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17): 7003-8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637741/
2015
A High Level of Intestinal Alkaline Phosphatase Is Protective Against Type 2 Diabetes Mellitus Irrespective of Obesity, Malo, EBioMedicine, 1December 2015, https://pubmed.ncbi.nlm.nih.gov/26844282/ citations: 87
2021
In a 5-year prospective cohort human study, Dr. Malo and his team proved, “IAP deficiency increases the risk of T2DM.” Malo et al., BMJ Open Diabetes Res Care. 2022 Jan:10(1)e002643; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796214/ The American Diabetes Association and the British Medical Journal jointed published the BMJ Open Diabetes Res Care journal article.

Our Gallery

Leadership Award

Dr. Biplab Malo – Outstanding Leadership Award | Health 2.0 Conference | USA Summer 2023

Dr. Biplab Malo, Founder & CEO of STAPGEN LLC, shares his transformative experience of being recognized with Outstanding Leadership Award at the Summer Edition of the Health 2.0 Conference, USA on July 10-12, 2023.
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Address
492 Summer Ave, Reading, Massachusetts
01867, United States.
Contact
+19789444197
info@stapgen.com
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